Regional 6 Engineer: Mike Smith, mike.smith@education.ky.gov
Region 6 KySTE Representative: Rhonda Thompson
| District | CIO / DTC Name | |
| Adair County | Jason Rector | |
| Barbourville Independent | Jeff Banfield | |
| Bell County | David Smith | |
| Berea Independent | Daniel Montoya | |
| Campbellsville Independent | Steven Gumm | |
| Casey County | Alejandra Woodrum | |
| Clay County | Kristi Woods | |
| Clinton County | Justin Mercer | |
| Corbin Independent | Kasey Trosper | |
| East Bernstadt Independent | Amanda Ball | |
| Estill County | Jeremy Simpson | |
| Garrard County | Chris Lang | |
| Harlan County | Brent Chitwood | |
| Harlan Independent | Charles Morton | |
| Jackson County | Rhonda Thompson | |
| Knox County | Kevin Parsons | |
| Laurel County | Mike Burns | |
| Lincoln County | Tracy Griffin | |
| Madison County | Ben Burnett | |
| McCreary County | Angela Corder | |
| Middlesboro Independent | David Sowders | |
| Model Laboratory Schools at EKU | Tim Hoover | |
| Pineville Independent |
|
|
| Pulaski County | Teresa Nicholas | |
| Rockcastle County | Brandon Reynolds | |
| Russell County | Chris Bell | |
| Science Hill Independent | Debbie Hill | |
| Somerset Independent | Mike Reynolds | |
| Taylor County | Kyle Arnett | |
| Wayne County | Valerie Hutchinson | |
| Whitley County | Kevin Anderson | |
| Williamsburg Independent | Grant Henderson |